ABSTRACT

The goal of this study was to investigate the occurrence and distribution of hyperdontia, hypodontia (which

includes mesiodens and fused teeth), talon cusps, microdontia (which includes peg-shaped lateral incisors), and

macrodontia in patients attending private dental clinics in Gharyan, Libya. During ordinary patient

examinations, the inquiry was undertaken clinically and radiographically. A total of 1219 participants were

included in the study (358 males and 861 females). 57 of patients had dental anomalies in the percentage of

(4.67%), 21 patients (1.72%) had missing teeth, 15 of them had one missing permanent tooth and 6 patients had

two missing permanent teeth (the lower 2nd premolar was the most tooth loss 0.49%). In addition, the study

showed that 16 patients had supernumerary teeth, 10 patients had microdontia and 7 patients had macrodontia,

whereas, two patients had talon cusp. Early detection of a treatable abnormality is critical in developing a

thorough treatment strategy for the patient. Some of the unpleasant impact should be avoidable. In some

circumstances; functional, cosmetic, and occlusal discord can be detected early enough to warrant interpret of

sessional consultation and treatment.

KEYWORDS: dental anomalies; hypodontia; microdontia; macrodontia

Phase I intervention in a skeletal

Class III case can involve

maxillary traction with a facemask,

often combined with rapid

maxillary expansion, followed by

orthodontic correction using Class

III mechanics.1 After cessation of

growth, however, treatment options

may be limited to surgical orthodontic

therapy.2,3 Although surgical treatment might produce

the best results, many patients reject

this option due to apprehension,

cost, or esthetic concerns.4-6

Orthodontic camouflage treatment

is possible in borderline cases, but

it is difficult to decompensate the

dentition and correct the occlusion

without jeopardizing the dentalperiodontal

equilibrium.

The most common antibiotics prescribed by dentists for dental infections in Gharyan city and neighbour regions

Abstract

Purpose: The purpose of this study was to evaluate the fitness of mandibular Kennedy class I PEEK removable partial dentures fabricated with various techniques.

Materials and Methods: Six patients were selected for this study with maxillary completely edentulous arch against mandibular distal extension ridges posterior to canine teeth. each patient was randomly given the following frameworks in a crossover design; Group I: All patients were received PEEK frameworks fabricated by milling via CAD-CAM technique (PEEK disc were used). Group II: All patients were received PEEK frameworks fabricated by injection molding technique (Granular form of medical grade PEEK). For each framework (milled & injected), the fitness evaluation were done by measuring the gap between the framework and oral structures by evaluation the thickness of light body poly vinyl- siloxane impression material.

Results: The mean overall and site specific values of Gap distance beneath frameworks fabricated by CAD-CAM technique was significantly higher than the mean values of Gap distance in frameworks fabricated by injection technique.

Conclusion: Within the limitations of this short-term clinical study it was concluded that: 1) The fitness of both techniques of the RPD PEEK BioHPP frameworks manufacture were clinically accepted by the participants. 2) The RPD PEEK BioHPP frameworks manufactured by CAD / CAM was less fitness values than BioHPP frameworks constructed by Injection molding technique.

The type VI secretion system (T6SS) is a multi-protein complex that injects bacterial effector proteins into target cells. It is composed of a cell membrane complex anchored to a contractile bacteriophage tail-like apparatus consisting of a sharpened tube that is ejected by the contraction of a sheath against a baseplate. We present structural and biochemical studies on TssA subunits from two different T6SSs that reveal radically different quaternary structures in comparison to the dodecameric E. coli TssA that arise from differences in their C-terminal sequences. Despite this, the different TssAs retain equivalent interactions with other components of the complex and position their highly conserved N-terminal ImpA_N domain at the same radius from the centre of the sheath as a result of their distinct domain architectures, which includes additional spacer domains and highly mobile interdomain linkers. Together, these variations allow these distinct TssAs to perform a similar function in the complex.

placing anterior dental implant is a challenging procedure for dental professional

TssA is a core component of the type VI secretion system, and phylogenetic analysis of TssA subunits from different species has suggested that these proteins fall into three distinct clades. Whilst representatives of two clades, TssA1 and TssA2, have been the subjects of investigation, no members of the third clade (TssA3) have been studied. Constructs of TssA from Burkholderia cenocepacia, a representative of clade 3, were expressed, purified and subjected to crystallization trials. Data were collected from crystals of constructs of the N-terminal and C-terminal domains. Analysis of the data from the crystals of these constructs and preliminary structure determination indicates that the C-terminal domain forms an assembly of 32 subunits in D16 symmetry, whereas the N-terminal domain is not involved in subunit assocation.

Abstract

Objectives: The goal of this study was to determine the correlation of clinicopathological factors and the up-regulation of Int-8 receptors and vascular endothelial growth factor (VEGF) expression in oral squamous cell carcinoma (OSCC).

Materials and Methods: Clinical data (age, gender, size of the tumor, location of the tumor, lymph nodes status,..) were collected from 20 patients with OSCC, tabulated and statistically analyzed (SPSS17).Immunohistochemical stainings of Int-8 receptors, CXCR1 and CXCR2 (united states biological, United Bio, USA) and VEGF (Abcam, Cambridge, MA, USA) were done.

Results: Our immunohistochemical study demonstrated: 1)expression of Int-8 receptors in all cases of OSCC with variable intensities, 2) high-level staining of VEGF In poorly differentiated and invasive oral squamous cell carcinoma. Significant correlation was observed between immunohistochemical expression of Int-8 receptors, VEGF and histologic differentiation and clinical stages(Analysis of variance ANOVA, P<0.05).

Conclusion: Our findings suggest that the reactivity to Int-8 receptors

observed in OSCC cases could be used as a parameter for tumor aggressiveness and as potential prognostic marker. Also, up-regulation of VEGF may play a role in the angiogenesis and progression of oral squamous cell carcinoma.

The effect of the duration of cigarette smoking on liver function