Abstract

Complete dentures remain an essential treatment option for edentulous patients, especially in regions where implant-supported prostheses are limited. Successful prosthodontic outcomes require systematic execution of clinical steps, including patient examination, impression taking, custom tray fabrication, jaw relation recording, try-in, and post-insertion management. This study aimed to assess the knowledge of complete denture fabrication among fourth-year dental students. A descriptive cross-sectional design was employed among 37 students (94.9% response rate) enrolled in 2024 at the Department of Prosthodontics, Faculty of Oral and Dental Medicine, Gharyan University. Data were collected using a validated, self-administered questionnaire covering patient assessment, primary and final impressions, custom tray design, jaw relation records, occlusal plane orientation, articulator use, try-in procedures, and post-insertion care, and analyzed descriptively.

All students (100%) reported performing histories, oral examinations, primary impressions with alginate, and centric relation registration. Knowledge gaps were observed in advanced procedures: 75.7% selected light-cure acrylic for custom trays, awareness of spacers, stops, and relief holes was limited, polyvinylsiloxane was the most frequently used final impression material (62.2%), yet 59.5% disinfected impressions improperly with water alone. None used a face bow or semi-adjustable articulators, relying solely on non-adjustable types. Students demonstrated solid foundational knowledge of basic procedures; however, deficiencies in custom tray design, post-palatal seal determination, impression disinfection, and articulator use indicate a need for enhanced clinical teaching and practical training to meet current prosthodontic standards.

Keywords. Complete Denture, Dental Students, Prosthodontics, Impression Technique.

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الملخص العربي الملف الوبائي والنسيجي المرضي ألورام الفم والرأس والرقبة في المعهد الوطني للسرطان: تحليل استعادي لمدة خمس سنوات )2020-2024) المقدمة ًرا في العالم، وتتمتع بمعدالت بقاء منخفضة تُعّد سرطانات الشفة وتجويف الفم من أكثر األورام الخبيثة انتشا على قيد الحياة رغم التقدم العالجي. في ليبيا، ال تزال البيانات الوبائية حول أورام الفم والرأس والرقبة محدودة. هدفت هذه الدراسة إلى توصيف الوضع الوبائي والنسيجي المرضي لهذه األورام على مدى خمس سنوات في المعهد الوطني للسرطان في صبراتة، من عام 2020 إلى عام 2024. ا جريت مراجعة بأثر رجعي لجميع حاالت السرطان والساركوما ال ُمثبتة نسيجيًا في تجويف الفم ُ لطريقة: أ والرأس والرقبة، والمسجلة في أرشيفات المعهد الوطني للسرطان. استُخلصت البيانات الديموغرافية للمرضى )اإلصدار 2.0.4 )Rالعمر والجنس(، وموقع الورم، والتشخيص النسيجي المرضي. ُحللت البيانات باستخدام لحساب متوسط العمر، وتوزيع الجنس، والتكرارات الخاصة بالموقع، والنسب السنوية ألورام الفم مقارنةً بإجمالي حاالت السرطان حالة سرطان ُمبل 48 حالة )59.0 )%منها ّ النتائج: من بين 152,8 غ عنها على مدار خمس سنوات، كانت أورا ًما فموية. تراوحت نسب األورام الفموية السنوية بين 34.0 %عام 2020 و83.0 %عام 2023 .تألفت ذكًر 58 )%و20 أنثى )42 ،)%بنسبة ذكور إلى إناث بلغت 1:4.1 .كان متوسط عمر المجموعة من 28 ا ) عا ًما(. كان اللسان أكثر المناطق تأث ًر )5.42 ،)%يليه الفك العلوي المرضى 2.54 عا ًما )النطاق: 12-89 ا )15 )%والبلعوم األنفي )5.12 .)%شكّل سرطان الخاليا الحرشفية )%69) SCC من الحاالت، وسرطان الغدد 19 ،%والساركوما 12 .%ومن بين حاالت سرطان الخاليا الحرشفية، بلغت نسبة الذكور 55 .% االستنتاج: شكلت أورام الفم والرأس والرقبة أقل من 1 %من جميع حاالت السرطان في المعهد الوطني للسرطان خالل الفترة 2020-2024 ،حيث أصابت بشكل رئيسي كبار السن من الذكور، وغالبًا ما شملت سرطان الخاليا الحرشفية اللسان. تؤكد هذه النتائج على ضرورة إجراء فحص ُمستهدف في المواقع التشريحية والفئات الديموغرافية عالية الخطورة. ينبغي أن تُدمج الدراسات المستقبلية عوامل الخطر السلوكية والبيئية لتوجيه استراتيجيات الوقاية والكشف المبكر. الكلمات المفتاحية: أورام الفم - سرطان الرأس والرقبة - سرطان الخاليا الحرشفية - التحليل بأثر رجعي - علم الاوبئة

Abstract Background: Cancers of the lip and oral cavity rank among the world’s most prevalent malignancies and carry poor survival rates despite therapeutic advances. In Libya, epidemiological data on oral and head‐and‐neck tumors remain limited. This study aimed to characterize the five‐year epidemiological and histopathological profile of these tumors at the National Cancer Institute (NCI), Sabratha, from 2020 to 2024. Methods: A retrospective review was conducted of all histologically confirmed carcinomas and sarcomas of the oral cavity, head, and neck recorded in the NCI archives. Patient demographics (age, sex), tumor site, and histopathologic diagnosis were extracted. Data were analyzed using R (v4.0.2) to calculate mean age, gender distribution, site‐specific frequencies, and annual proportions of oral tumors relative to total cancer cases. Results: Among 8,152 cancer cases reported over five years, 48 (0.59%) were oral tumors. Annual oral tumor proportions ranged from 0.34% in 2020 to 0.83% in 2023. The cohort comprised 28 males (58%) and 20 females (42%), with a male-to-female ratio of 1.4:1. The mean patient age was 54.2 years (range: 12–89). The tongue was the most affected site (42.5%), followed by maxilla (15%) and nasopharynx (12.5%). Squamous cell carcinoma (SCC) constituted 69% of cases, adenocarcinoma 19%, and sarcoma 12%. Among SCCs, 55% occurred in males. Conclusion: Oral and head‐and‐neck tumors comprised less than 1% of all cancers at NCI during 2020–2024, predominantly affecting older males and most frequently involving the tongue as SCC. These findings underscore the need for targeted screening in high‐risk anatomical sites and demographic groups. Future studies should integrate behavioral and environmental risk factors to inform prevention and early‐detection strategies. Keywords:)Oral Tumors-Head-and-neck cancer-Squamous cell carcinomaRetrospective analysis-Epidemiology(

Abstract 

Dental caries is a widespread infectious disease influenced by bacterial activity, dietary factors, and host 

susceptibility. Community water fluoridation has been a key public health measure for caries prevention, 

particularly in children. The optimal fluoride concentration in drinking water (0.7 mg/L) balances caries 

reduction with minimal fluorosis risk. This study assessed fluoride levels in drinking water and their 

correlation with dental caries in primary school children in Gharyan, Libya. A cross-sectional study was 

conducted on 350 children (aged 7–10 years) from urban and rural schools in Gharyan. Water samples from 

five stores and one groundwater source were analyzed for fluoride concentration using an ion-selective 

electrode. Dental caries was assessed using the dmft/DMFT index. Fluoride levels in water stores were 

negligible (0.0–0.1 mg/L), while unfiltered groundwater exhibited high concentrations (6.0–7.0 mg/L), 

exceeding WHO guidelines (1.5 mg/L). The low fluoride availability in most drinking sources suggests 

limited caries-preventive effects from water fluoridation in this region. The study highlights insufficient 

fluoride exposure in Gharyan’s public water supply, potentially contributing to higher caries prevalence. 

Further research is needed to evaluate alternative fluoride delivery methods and assess groundwater safety 

to optimize oral health outcomes.

Keywords. Fluoride Concentration, Drinking Water, Dental Caries, Primary School.

Abstract The aim of this study was to estimate the levels of TNF-α in serum and gingival crevicular fluid, in patients with chronic periodontitis (CP), before and after phase I therapy with subgingival delivery of Hyaluronic acid (Gengigel Gel). A total of thirty subjects were included in this study; 20 CP patients as a study group (group I) and 10 systemically healthy subjects with clinically healthy gingiva as a control group (group II). The nonsurgical periodontal therapy (SRP) + HA gel were done in group I. Periodontal parameters, including PI, GI, BOP, PD and the CAL, were recorded. GCF and serum were collected from all individuals included in the study; the first sample was collected from all groups (study and control) before treatment. The second sample was collected 4 weeks after subgingival delivery of Hyaluronic acid & phase I therapy from group I. Levels of TNF-α in GCF and serum were quantified using ELISA. The results showed a statistically significant reduction in total levels of TNF-α in serum and TNF-α in GCF in study group after application of Hyaluronic acid with phase I therapy. Results also showed all clinical parameters were significantly improved after application of Hyaluronic acid with phase I therapy in groups I (p<0.001). Scaling and root planing (SRP) is the mainstay of treatment of periodontal diseases, furthermore subgingival application of Hyaluronic acid gel with SRP were effective in improving clinical parameters in CP patients. TNF-α level in serum and GCF are reduced after phase I therapy with application of Hyaluronic acid.

Abstract

The aim of this study was to investigate the prevalence, causes of tooth loss, and associated factors among the older adult population attending dental clinics in the city of Gharyan in Libya. A descriptive cross-sectional study conducted among adults who came to private clinics in the city of Gharyan in Libya. There were 160 patients participated in the study. Those that met the inclusion criteria had their data collected via self-administered questionnaires. Computer-assisted techniques used to examine the data (IPMSPSS). The results of the present study indicated that the major cause of tooth loss was dental caries (65.56%), followed by periodontal disease (11.88%). and more teeth loss was in the female than male and increased tooth loss with aging. In conclusion, there was a high prevalence of tooth loss. Females lost more teeth than males. Increased proportion of tooth loss seen in the elderly population.

كان الهدف من هذه الدراسة هو التحقيق في انتشار وأسباب فقدان الأسنان والعوامل المرتبطة بها بين كبار السن الذين يرتادون عيادات الأسنان في مدينة غريان في ليبيا. أجريت دراسة وصفية مقطعية بين البالغين الذين جاءوا إلى العيادات الخاصة في مدينة غريان في ليبيا. شارك في الدراسة 160 مريضًا. تم جمع بيانات أولئك الذين استوفوا معايير الإدراج من خلال استبيانات ذاتية الإدارة. تم استخدام تقنيات بمساعدة الكمبيوتر لفحص البيانات (IPMSPSS). أشارت نتائج الدراسة الحالية إلى أن السبب الرئيسي لفقدان الأسنان كان تسوس الأسنان (65.56٪)، يليه مرض اللثة (11.88٪). وكان فقدان الأسنان أكثر لدى الإناث منه لدى الذكور وزيادة فقدان الأسنان مع تقدم العمر. في الختام، كان هناك انتشار كبير لفقدان الأسنان. فقدت الإناث أسنانًا أكثر من الذكور. زادت نسبة فقدان الأسنان لدى كبار السن

ABSTRACT

INTRODUCTION: Malignancy is regarded as a potentially fatal disorder that can impact human health globally. More than 90% of all oral cavity malignancies that have been detected are invasive oral squamous cell carcinomas (OSCCs). Patients having OSCC still have an extremely poor survival rate, even though medical therapy has advanced significantly. Medicinal plants have been the subject of recent scientific research. Capparis spinosa L. (CS) is among the prominent plants found across the Mediterranean region.According to phytochemical analysis, CS leaves are considered to be a promising therapeutic plant since they are an essential spring of bioactive substances such as flavonoids and phenolic acids. Research has indicated that CS extract exhibits anti-carcinogenic properties against numerous forms of cancer.

OBJECTIVE: The current research was to the evaluation of the anti-carcinogenic effect of the ethanolic extract of CS leaves on SCC-4 cell lines contrasted with both the untreated cancer cell lines and Cisplatin treated.

MATERIALS AND METHODS: This work comprised an in vitro investigation. SCC-4 cell line was separated into 3 groups: group 1 was considered as negative control (untreated), group 2 was positive control (Cisplatin-treated), and group 3 (treated with CS leaves extract). Viability, proliferation and apoptosis assays were performed to evaluate the possible therapeutic effect of the CS leaves extract in duration of 48 hours.

RESULTS: Treating SCC-4 cell line with the extract of CS leaves has shown that the viability effect was in a dose-dependent fashion. The IC50 or the half-maximal inhibitory concentration was equal to 176.3μg/ml. Also, CS treatment has elevated the apoptotic cells’ percentage and decreased SCC-4 cells proliferation rate in compare to the untreated cancer cell lines and Cisplatin

action.

CONCLUSION: the extract of CS leaves may have a prominent anti-cancerous effect on OSCC.

KEYWORDS: Oral squamous cell carcinoma, Capparis spinosa L., Viability, Proliferation, Apoptosis.

Running Title: Anti-carcinogenic effect of Capparis spinosa L. on SCC-4

The dentigerous cyst is a developmental odontogenic asymptomatic cyst, that is associated with the crown of an

unerupted or impacted tooth. Early diagnosis is important to avoid any future complications and choose the best

treatment option. The purpose of this case report is to describe the management of a dentigerous cyst related to

lower second molar in a young female patient using orthodontic traction as a conservative treatment approach.

This procedure helps to spare the patient an unnecessary surgical excision procedure and the associated excessive

bone removal for a safety margin, stimulates bone healing and promotes the eruption of the cyst-associated tooth.

Keywords Dentigerous cyst, Decompression, Orthodontic traction

الدراسة شملت معدل انتشار الامراض الفموية للغشاء المخاطي ضمن المصابين بمرض السكري في منطقة غريان بالجبل الغربي